Studying pancreatic islet immunometabolism, immune–metabolic crosstalk, beta-cell states, and epigenetic regulation in diabetes.
The Dror Laboratory studies the pancreatic islet as a dynamic tissue environment where immune cells, beta cells, metabolic signals, inflammation, and chromatin regulation interact.
Core directions connecting diabetes, pancreatic islets, immune signaling, beta-cell states, and epigenetics.
Mapping immune cells around pancreatic islets and studying their role in tissue maintenance, inflammation, and disease.
Investigating communication between beta cells, immune cells, cytokines, and metabolic stress pathways in the islet niche.
Exploring beta-cell heterogeneity, chromatin regulation, and mechanisms linked to diabetes progression.
Diabetes is a spectrum of diseases, but a shared feature is dysfunction of the body’s insulin producers: the pancreatic islets. Understanding how inflammation, epigenetics, and beta-cell function interact may reveal new mechanisms and future therapeutic strategies.
We welcome inquiries from students, postdocs, researchers, and collaborators interested in diabetes, pancreatic islets, immunology, metabolism, and epigenetic regulation.
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